Monday, June 24, 2013

AVMA July 2013 Issue Addresses Stability of Three Commonly Compounded Extemporaneous Enrofloxacin Suspensions

Stability of three commonly compounded
extemporaneous enrofloxacin suspensions
for oral administration to exotic animals
Enrofloxacin has been used in many exotic animal species, but
no oral suspensions of enrofloxacin are currently commercially
available. Thus, compounded formulations are often used. In
a study of the stability of 3 extemporaneous oral suspensions
of enrofloxacin mixed with readily available flavoring vehicles
and stored at room temperature in amber vials, the enrofloxacin
concentration in all 3 formulations was retained within acceptable limits (ie, 90% to 110% of the nominal concentration) for
up to 56 days. Subjectively, cherry syrup flavoring was better at
masking the smell and taste of enrofloxacin than was corn syrup
or liquid sweetener. See PAGE 85

quoted from here

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